Lipid Modifications in Cilia Biology
نویسندگان
چکیده
منابع مشابه
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Cilia and flagella are microtubule-based appendages extending from the basal body of most eukaryotic cells, and are classified as either motile or primary. Motile cilia or flagella can be found on many cells such as Chlamydomonas, sperm, and respiratory tract epithelial cells. This type of cilia is responsible for movement of the cell itself or generation of fluid flow. In contrast, primary cil...
متن کاملLipid modifications of proteins
Lipid modifications of proteins (Fig. 1) are widespread and functionally important in eukaryotic cells. For example, many intracellular proteins such as the signal-transducing heterotrimeric GTP-binding proteins (G proteins) and the Ras superfamily of G proteins are modified by 14or 16-carbon fatty acids and/or 15or 20-carbon isoprenoids. Also, a variety of cell surface proteins such as acetylc...
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Is it fair to say that Micromalthus is an ancient, primitive beetle? Many of Micromalthus’ anatomical characters are indeed primitive, in the sense of resembling the most recent ancestor it shares with other beetles, but of course its life cycle is anything but. No one thinks the ancestral beetle — or the ancestors of any other living beetles — had Micromalthus’ bizarre genetic and developmenta...
متن کاملThematic review series: lipid posttranslational modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I.
More than 100 proteins necessary for eukaryotic cell growth, differentiation, and morphology require posttranslational modification by the covalent attachment of an isoprenoid lipid (prenylation). Prenylated proteins include members of the Ras, Rab, and Rho families, lamins, CENPE and CENPF, and the gamma subunit of many small heterotrimeric G proteins. This modification is catalyzed by the pro...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2019
ISSN: 2077-0383
DOI: 10.3390/jcm8070921